| Accession | GMS-65-4
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| Title | ABC (activity-by-contact) model of enhancer-promoter regulation |
| Submit date | 2023-06-02 17:19:58 |
| Last update date | 2023-06-02 18:33:14 |
| Contact | GMSuite GENOMEMODALITY gmsuite AT hgc.jp The University of Tokyo |
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| Total file size | 444.50 KB |
| Keywords | Enhancer |
| Experiment type | GM Suite https://gmsuite.hgc.jp/jbrowse2/index.php?config=ABC_hg19_config.json ABC Enhancer-Gene Connections https://flekschas.github.io/enhancer-gene-vis |
| Summary | .... This activity-by-contact model allows us to construct genome-wide maps of enhancer-gene connections in a given cell type, on the basis of chromatin state measurements. Together, CRISPRi-FlowFISH and the activity-by-contact model provide a systematic approach to map and predict which enhancers regulate which genes, and will help to interpret the functions of the thousands of disease risk variants in the noncoding genome.... |
| Citation(s) | https://pubmed.ncbi.nlm.nih.gov/31784727/ |
| Organism | Human |
| Cell (Tissue) | not applicable |
| Protocol | |
| Data processing |
