NANOG (Nanog homeobox)
Organism homo_sapiens 
Gene type protein-coding
Summary The protein encoded by this gene is a DNA binding homeobox transcription factor involved in embryonic stem (ES) cell proliferation, renewal, and pluripotency. The encoded protein can block ES cell differentiation and can also autorepress its own expression in differentiating cells. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2015]
Description homeobox protein NANOG
homeobox transcription factor NANOG
homeobox transcription factor NANOG-delta 48
NCBI Gene 79923 
ID ENSG00000111704 jMorp:79923 GDC:ENSG00000111704 GeneCards:NANOG 
Uniprot
Locus:Strand chr12:7789401-7799145:+ [NC_000012.12]
AlphaFold

Expression
GM Suite Record
GMS-65-113
Intra-chromosomal Hi-C contacts in mESC

1043 
Flexibility and Viscoelasticity
PHiC_FlexVisco.png (1.13 MB)
766  Domains PHiC JBrowse
Intra-chromosomal Hi-C contacts (Rep 2)
Merge2.intra.MQ30.ValidPairs.hic (1.79 GB)
mm10 Hi-C
765  PHiC: Stiffness JBrowse
Intra-chromosomal Hi-C contacts (Rep1)
Merge1.intra.MQ30.ValidPairs.hic (1.69 GB)
mm10 Hi-C

PHi-C2 Nanog Flexibility 
Viscoelasiticity Genome DNA Stiffness 
Nuclear-scale 
GMS-83-2
In silico nanoscope to study the interplay of genome organization and transcription regulation

687 
Cluster 3
Eq_Struct_Cluster3.cif (262.66 MB)
690 
Cluster 5
Eq_Struct_Cluster5.cif (262.66 MB)
689 
Cluster 1
Eq_Struct_Cluster1.cif (262.66 MB)
688 
Cluster 4
Eq_Struct_Cluster4.cif (262.66 MB)
674 
ReadMe.txt
READ_ME.txt (1.74 KB)
686 
Cluster 2
Eq_Struct_Cluster2.cif (262.66 MB)
683 
Cluster 2
Eq_Cluster2_rock.mp4 (38.23 MB)
682 
Cluster 4
Eq_Cluster4_rock.mp4 (34.44 MB)
681 
Cluster 1
Eq_Cluster1_rock.mp4 (25.16 MB)
680 
Cluster 3
Eq_Cluster3_rock.mp4 (33.76 MB)
679 
Cluster 5
Eq_Cluster5_rock.mp4 (16.92 MB)
678 
Cluster 1
Eq_Cluster1_zoomin.mp4 (5.45 MB)
675 
ZIP (Cif, Gro, Pse)
Struct_Cluster1-5.zip (1.07 GB)

Nanog gene Transcription factor RNA polymerase II 
Chromatin Nanoscale 
GMS-97-2
Transcription-coupled changes in genomic region proximities during transcriptional bursting

980 
Genome dynamics in Nanog inactive state simulated by PHi-C
adn0020_movie_s3.mp4 (6.01 MB)
981 
Genome dynamics in Nanog active state simulated by PHi-C
adn0020_movie_s2.mp4 (5.37 MB)

PHi-C2 Genome DNA Modeling 
Mesoscale Brownian dynamics Nanog 
Genome Browser GMS UCSC